Signal Transduction Reagents and Kits
Thermo Scientific Chemicals Cathepsin G Inhibitor I
CAS: 429676-93-7 Molecular Formula: C36H33N2O6P
Thermo Scientific Chemicals p21-Activated Kinase Inhibitor III, IPA-3
CAS: 42521-82-4 Molecular Formula: C20H14O2S2 Synonym: PAK Inhibitor III; 1,1′-Disulfanediylbis(naphthalen-2-ol)
Thermo Scientific Chemicals IGF-1R Inhibitor, PPP
CAS: 477-47-4 Molecular Formula: C22H22O8 Molecular Weight (g/mol): 414.41 InChI Key: YJGVMLPVUAXIQN-HAEOHBJNSA-N Synonym: Insulin-like Growth Factor-1 Receptor Inhibitor; Picropodophyllin IUPAC Name: (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0³,⁷.0¹¹,¹⁵]hexadeca-1,3(7),8-trien-12-one SMILES: COC1=CC(=CC(OC)=C1OC)[C@H]1[C@H]2[C@H](COC2=O)[C@@H](O)C2=CC3=C(OCO3)C=C12
Thermo Scientific Chemicals Aurora Kinase/Cdk Inhibitor
CAS: 443797-96-4 Molecular Formula: C15H12F2N6O3S Molecular Weight (g/mol): 394.36 InChI Key: KDKUVYLMPJIGKA-UHFFFAOYSA-N Synonym: 4-(5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-ylamino)-benzenesulfonamide; IUPAC Name: 4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide SMILES: NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F
Thermo Scientific Chemicals Kallikrein Inhibitor
CAS: 97145-43-2 Molecular Formula: C35H55N11O9 Synonym: N-Acetyl-Pro-Phe-Arg-Ser-Val-Gln-NH{2}; KKI 5
Thermo Scientific Chemicals Midostaurin
CAS: 120685-11-2 Molecular Formula: C35H30N4O4 Synonym: PKC412; 4'-N-Benzoylstaurosporine
Thermo Scientific Chemicals Calpain Inhibitor III, 95+%
CAS: 88191-84-8 Molecular Formula: C22H26N2O4 Molecular Weight (g/mol): 382.46 InChI Key: NGBKFLTYGSREKK-PMACEKPBSA-N Synonym: MDL; Z-Val-Phe-CHO IUPAC Name: benzyl N-[(1S)-2-methyl-1-{[(2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl}propyl]carbamate SMILES: CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C=O
Thermo Scientific Chemicals gamma-Secretase Inhibitor I
CAS: 133407-83-7 Molecular Formula: C26H41N3O5 Molecular Weight (g/mol): 475.63 InChI Key: RNPDUXVFGTULLP-UHFFFAOYNA-N Synonym: Z-Leu-Leu-Nle-CHO (Nle = Norleucine); IUPAC Name: benzyl N-[3-methyl-1-({3-methyl-1-[(1-oxohexan-2-yl)carbamoyl]butyl}carbamoyl)butyl]carbamate SMILES: CCCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O
Cis-5,8,11,14,17-Eicosapentaenoic Acid, PROMO, Thermo Scientific Chemicals
CAS: 10417-94-4 Molecular Formula: C20H30O2 Synonym: EPA; Timnodonic acid
Marimastat, 98%, PROMO, Thermo Scientific Chemicals
CAS: 154039-60-8 Molecular Formula: C15H29N3O5 Synonym: (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl] propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide; BB2516
SB 202190, 99+%, PROMO, Thermo Scientific Chemicals
CAS: 152121-30-7 Molecular Formula: C20H14FN3O Synonym: 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole
MilliporeSigma™ Simplicon™ Reprogramming RNA (OKSG)
For use as transfection reagent.
Promega ADP-Glo™ Kinase Assay
ADP-Glo™ Kinase Assay is a luminescent kinase assay that measures ADP formed from a kinase reaction; ADP is converted into ATP, which is converted into light by Ultra-Glo™ Luciferase. The luminescent signal positively correlates with kinase activity.
Promega NAD/NADH-Glo™ Assay
The NAD/NADH-Glo™ Assay is a bioluminescent, homogeneous single-reagent-addition assay for detecting total oxidized and reduced nicotinamide adenine dinucleotides and determining their ratio in biological samples or in defined enzyme reactions.
Promega GSH/GSSG-Glo™ Glutathione Assay
The GSH/GSSG-Glo™ Assay is a luminescence-based system for the detection and quantification of total glutathione (GSH +GSSG), GSSG and GSH/GSSG ratios in cultured cells.